Prevalence of comorbidities and its impacts in Hospitalized patients with COVID-19
AbstractObjective: The purpose of this study is to evaluate the prevalence of comorbidities in hospitalized COVID-19 patients and its effects on the severity of the disease. The coronavirus pandemic has been a challenging problem for health care systems since December 2019.
Methods: This was a retrospective, cross-sectional study analyzing data related to the epidemiological characteristics of COVID-19 patients admitted to Razi Hospital in Ahvaz, Iran from November 2020 to February 2021. The data on patient demographic characteristics including age, gender, and underlying diseases were collected from patient records. Patients whose data were unavailable or incomplete were excluded from the study.
Results: The mean age of all of the 730 patients studied was 56.30±16.36 years, and 53.7% of them were men. Nearly 40% of the patients reported more than one comorbidity, with diabetes mellitus being the most frequent one (37.5%) followed by hypertension (35.3%) and ischemic heart disease (24.9). In addition, 21.5% of the patients required intensive care unit admission. Finally, 11.9% of the patients had respiratory distress and became intubated, and approximately 13.6% of the patients died. Hyperlipidemia, liver failure, tuberculosis, and elevated inflammatory biomarkers are risk factors for ICU admission and death.
Conclusion: we found that male gender, older age, hyperlipidemia, liver failure, TB, having more than one comorbidity, and elevated inflammatory biomarkers were significantly associated with the risk of severe COVID-19 disease.
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