A study on the prevalence and the risk factors of hepatitis B virus infection in Kurdistan Region, Iraq: A multicenter study

Prevalence and the risk factors of HBV

  • Nawfal R Hussein Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho Kurdistan Region, Iraq
  • Dildar H Musa Department of Surgery, College of Medicine, University of Duhok, Kurdistan region, Iraq
  • Dawan Jamal Hawezy Department of Surgery, College of Medicine, University of Koya, Kurdistan region, Iraq
  • Ferhad MR Ahmed Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho Kurdistan Region, Iraq
  • Fatma Kamal Khalid Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho Kurdistan Region, Iraq
  • Ibrahim A Naqid Department of Biomedical Sciences, College of Medicine, University of Zakho, Kurdistan Region, Iraq. http://orcid.org/0000-0002-7223-2690
  • Mahde Saleh Assafi 4Department of Biology, College of Science, University of Duhok, Kurdistan region, Iraq

Abstract

Objectives: The aims of this study were to determine the prevalence of HBV infection and investigate the HBV-related risk factors in the Kurdistan region of Iraq.
Methods: Sera samples were collected from 3423 patients visiting three centers and tested for HBV positivity by enzyme-linked immunosorbent assay. A questionnaire was prepared and used by the volunteers who collected data, including age, marital status, and different HBV-related risk factors, through face-to-face interviews.
Results: The mean age of the recruited participants was 28.94 ± 11.17 years. In addition, 873/3423 (25.47%) were males, and 3024/3423 (88.34%) were married. Furthermore, HBV infection had a prevalence of 1.37% (47/3243). Multivariate analysis was conducted to identify the predictive factors of HBV infection, which revealed that a history of tattoos and age were predictive factors (p<0.05). We then stratified our data according to sex. No association was found between the various factors and HBV positivity in males. On the other hand, in females, a significant association was found between the history of tattoos or age and HBV positivity (p<0.05).
Conclusions: In conclusion, the prevalence of HBV infection was low. Our study showed that a history of tattooing and older age were predictive of HBV infection. Our results could be used as a basis for local elimination programs.
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References

1. El-Serag HB. Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma. Gastroenterology. 2012;142(6):1264-73.e1.
2. Igde F, Taskin H, Igde M, Yazici Z, Atilla A. Where we are in the fight against Hepatitis B Infection; Trends in Hepatitis B virus seroprevalence in Black Sea Region of Turkey. Nigerian Journal of Clinical Practice. 2018;21(1):87-92.
3. Alavian SM, Tabatabaei SV, Ghadimi T, Beedrapour F, Kafi-abad SA, Gharehbaghian A, et al. Seroprevalence of Hepatitis B Virus Infection and Its Risk Factors in the West of Iran: A Population-based Study. International Journal of Preventive Medicine. 2012;3(11):770-5.
4. Mohammed Abdullah S. Prevalence of Hepatitis B and C in Donated Blood from the Jazan Region of Saudi Arabia. The Malaysian Journal of Medical Sciences : MJMS. 2013;20(2):41-6.
5. Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B Virus Infection: Epidemiology and Vaccination. Epidemiologic Reviews. 2006;28(1):112-25.
6. Mohammed Saleem ZS, Naqid IA, Hussein NR, Mohammad SJ, Noaman JS, Haji RS, et al. The Prevalence of Hepatitis B and C Virus in Patients With End-Stage Kidney Disease on Regular Hemodialysis in Duhok, Iraq: A Brief Report. Avicenna J Clin Microbiol Infect. 2020;7(1):31-3.
7. Assafi MS, Ibrahim NM, Hussein NR, Taha AA, Balatay AA. Urinary bacterial profile and antibiotic susceptibility pattern among patients with urinary tract infection in duhok city, kurdistan region, Iraq. International Journal of Pure and Applied Sciences and Technology. 2015;30(2):54.
8. Hussein NR. Risk factors of hepatitis B virus infection among blood donors in Duhok city, Kurdistan Region, Iraq. Caspian journal of internal medicine. 2018;9(1):22.
9. Al – Juboury A, M. Salih H, AL- ASSADI M, Ali AM. Seroprevalence of Hepatitis B and C among Blood Donors in Babylon Governorate-Iraq. Medical Journal of Babylon 2010;7(1-2).
10. Hussein NR, Daniel S. A Study of Hepatitis B Virus Associated Risk Factors in Patients Attending Hepatitis Unit in Duhok City, Iraq. Archives of Clinical Infectious Diseases. 2017;12(3).
11. Li X, Zheng Y, Liau A, Cai B, Ye D, Huang F, et al. Hepatitis B virus infections and risk factors among the general population in Anhui Province, China: an epidemiological study. BMC Public Health. 2012;12(1):1-7.
12. Jafari S, Buxton JA, Afshar K, Copes R, Baharlou S. Tattooing and risk of hepatitis B: a systematic review and meta-analysis. Can J Public Health. 2012;103(3):207-12.
13. Galles NC, Liu PY, Updike RL, Fullman N, Nguyen J, Rolfe S, et al. Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1. The Lancet. 2021;398(10299):503-21.
14. Ozer A, Yakupogullari Y, Beytur A, Beytur L, Koroglu M, Salman F, et al. Risk factors of hepatitis B virus infection in Turkey: A population-based, case-control study. Hepat Mon. 2011;11(4):263-8.
15. Hussein NR, Haj SM, Almizori LA, Taha AA. The prevalence of hepatitis B and C viruses among blood donors attending blood bank in Duhok, Kurdistan region, Iraq. Int J Infect. 2017;4(1):e39008.
16. Jamal SA, Naqid IA, Hussein NR, Abdulqader SR, Nimet AA, Abdulkhdair HA, et al. The Prevalence of Hepatitis B and C Virus Infections in the Couples Attending a Premarital Screening Program in Zakho City, Kurdistan Region of Iraq. Zahedan J Res Med Sci. 2020;23(2):e99405.
17. Hussein NR, Saleem ZS, Ibrahim NM, Assafi MS, Daniel S. The Prevalence of HBV Infection in Renal Transplant Recipients and the Impact of Infection on Graft Survival. Acta Medica Iranica. 2019;57(6):381-4.
Published
2021-10-26
How to Cite
HUSSEIN, Nawfal R et al. A study on the prevalence and the risk factors of hepatitis B virus infection in Kurdistan Region, Iraq: A multicenter study. Journal of Contemporary Medical Sciences, [S.l.], v. 7, n. 5, oct. 2021. ISSN 2413-0516. Available at: <http://www.jocms.org/index.php/jcms/article/view/1037>. Date accessed: 07 dec. 2021. doi: https://doi.org/10.22317/jcms.v7i5.1037.