Association between Anti-Müllerian Hormone and other biomarkers with ovarian function in polycystic ovarian syndrome of Iraqi women

Authors

  • Huda Basim Al-Lami Department of Chemistry and Biochemistry, College of Medicine, University of Kerbala, Kerbala, Iraq.
  • Fadhil Jawad Al-Tu’ma Department of Chemistry and Biochemistry, College of Medicine, University of Kerbala, Kerbala, Iraq.
  • Wasan Ghazi Al-Safi Department of Gynecology and Obstetrics, College of Medicine, University of Kerbala, Kerbala, Iraq.

DOI:

https://doi.org/10.22317/jcms.v6i4.824

Keywords:

Anti-Müllerian hormone, Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH) and LH/FSH ratio

Abstract

Objectives: The current study aimed to investigate the role of of Anti-Müllerian hormone and other hormonal biomarkers and insulin resistance in pathogenesis of polycystic ovarian syndrome of Iraqi women with various ages and BMI.

Method: The sublects include 50 cases of polycystic ovarian syndrome obtained from gynecological and obstetric teaching hospital, Kerbala health directorate / Kerbala – Iraq and another 50 apparently healthy women as a control group. with age ranged between (18-37) years during the period from Dec. 2019 to June, 2020 which was divided into two groups depending upon their age; first group with age (18-27) years and the second with age (28-37) years, also they divided into three subgroups depending upon the body mass index, normal weight (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), obesity (30-34.9 kg/m2) and  measurement of various hormonal levels were performed including LH, FSH, insulin, insulin resistance, total testosterone and anti-müllerian hormone.

Results: A significant elevated levels of each of Anti-Müllerian hormone (AMH), insulin, LH, total testosterone, prolactin, fasting blood glucose, FBG and insulin resistance while, a non-significant differences was found in FSH levels in women with PCOS as compared with control group.

Conclusion: A significant high levels of the all hormonal parameters including anti-müllerian hormone, LH, prolactin and total testosterone  was found in women with PCOS as compared with the control, except the FSH values.

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Published

2020-08-26

How to Cite

Al-Lami, H. B., Al-Tu’ma, F. J., & Al-Safi, W. G. (2020). Association between Anti-Müllerian Hormone and other biomarkers with ovarian function in polycystic ovarian syndrome of Iraqi women. Journal of Contemporary Medical Sciences, 6(4), 168–175. https://doi.org/10.22317/jcms.v6i4.824

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