Effect of matrix rhythm therapy in Diabetic foot ulcer healing: A Case Report


  • Varun Naik Department of Cardiovascular and Pulmonary Physiotherapy, KAHER’s Institute of Physiotherapy, Belagavi, Karnataka, India.
  • Chandra Bahadur Khatri Department of Cardiovascular and Pulmonary Physiotherapy, KAHER’s Institute of Physiotherapy, Belagavi, Karnataka, India.
  • Ganesh BR Department of Cardiovascular and Pulmonary Physiotherapy, KAHER’s Institute of Physiotherapy, Belagavi, Karnataka, India




matrix rhythm therapy, Foot ulcer, case report


 Diabetic foot ulcer is one of the major complications following diabetes. In India, 15% of diabetic patient develop DFU once in their lifetime. Neuropathy associated with diabetes is a major factor in development of foot ulcer in such patients. Infection, peripheral arterial diseases, altered functions of white blood cells, stem cells and regenerating tissues and co-morbidities lead to delayed wound healing. Matrix rhythm therapy is a recent advancement in the field of Physiotherapy. It provides external oscillation that activates normal rhythm of cell that is between 8-12 Hz which improves cellular function within cell and extracellular matrix, enhancing tissue healing.

A 70 year female presented with infected diabetic foot ulcer on her right foot in out-patient department of KLE hospital. She had non-healing ulcer since one and half months and undergone conservative treatment of wound care along with strategies of diabetic foot care.

Clinical findings: Subject complained of Pain with score of 2 at rest and 6 while walking which was recorded on the basis of Visual Analogue Scale. Wound appeared ischemic and non-healing. On wound assessment, size of wound was 12mm in diameter and 6 mm depth. It was identified as Type D grade I on the basis of classification of wound provided by University of Texas Health Science center.

Intervention: Matrix rhythm therapy was applied on posterior aspect of leg region extending around wound area once a week for 5 weeks with treatment duration of one hour.

Result: Pain of the subject after 5 weeks of intervention was 0 at rest and 2 while walking on the basis of VAS. Size of wound decreased with dimension of 6mm in diameter and 2 mm depth and categorized as Type A grade 1.

Conclusion: Matrix rhythm therapy could be considered as adjunct in wound healing of diabetic foot ulcer.


1. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation. Part 1, Diagnosis and classification of diabetes mellitus. Geneva: World health organization; 1999.
2. Nathan DM. Long-term complications of diabetes mellitus. New England Journal of Medicine. 1993 Jun 10;328(23):1676-85.
3. Jeffcoate WJ, Harding KG. Diabetic foot ulcers. The lancet. 2003 May 3;361(9368):1545-51.
4. Ghosh P, Valia R. Burden of Diabetic Foot Ulcers in India: Evidence Landscape from Published Literature. Value in Health. 2017 Oct 1;20(9):A485.
5. Clayton W, Elasy TA. A review of the pathophysiology, classification, and treatment of foot ulcers in diabetic patients. Clinical diabetes. 2009 Apr 1;27(2):52-8.
6. Bowering CK. Diabetic foot ulcers. Pathophysiology, assessment, and therapy. Canadian Family Physician. 2001 May 1;47(5):1007-16.
7. Noor S, Zubair M, Ahmad J. Diabetic foot ulcer—a review on pathophysiology, classification and microbial etiology. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2015 Jul 1;9(3):192-9.
8. Falanga V. Wound healing and its impairment in the diabetic foot. The Lancet. 2005 Nov 12;366(9498):1736-43.
9. Apelqvist J, Larsson J, Agardh CD. Long‐term prognosis for diabetic patients with foot ulcers. Journal of internal medicine. 1993 Jun;233(6):485-91.
10. Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. Jama. 2005 Jan 12;293(2):217-28.
11. Piaggesi A, Schipani E, Campi F, Romanelli M, Baccetti F, Arvia C, Navalesi R. Conservative surgical approach versus non‐surgical management for diabetic neuropathic foot ulcers: a randomized trial. Diabetic Medicine. 1998 May;15(5):412-7.
12. Lipsky BA, Berendt AR, Deery HG, Embil JM, Joseph WS, Karchmer AW, LeFrock JL, Lew DP, Mader JT, Norden C, Tan JS. Diagnosis and treatment of diabetic foot infections. Clinical Infectious Diseases. 2004 Oct 1:885-910.
13. Bakker K, Apelqvist J, Schaper NC, International Working Group on the Diabetic Foot Editorial Board. Practical guidelines on the management and prevention of the diabetic foot 2011. Diabetes/metabolism research and reviews. 2012 Feb;28:225-31.
14. Stansby G, Avital L, Jones K, Marsden G. Prevention and management of pressure ulcers in primary and secondary care: summary of NICE guidance. Bmj. 2014 Apr 23;348:g2592.
15. Zhou K, Krug K, Brogan MS. Physical therapy in wound care: a cost-effectiveness analysis. Medicine. 2015 Dec;94(49).
16. The Matrix Concept in Practice – Dr. Randoll Institut • Gemeinnützige Gesellschaft für Matrix-Forschung und -Lehre mbH [Internet]. [20.04.2019]. Available from: https://www.dr-randoll-institut.de/en/matrix-konzept-in-der-praxis.
17. Ketan Bhatikar. Effect of Matrix Rhythm Therapy on Chronic Vein Dysfunction Deep Foot Ulcer: A Case Report. J Yoga & Physio. 2018; 6(5): 555696. DOI: 10.19080/JYP.2018.06.555696.
18. Sari Z, Polat MG, Özgül B, Aydoğdu O, Camcıoğlu B, Acar AH, Yurdalan SU. The application of matrix rhythm therapy as a new clinical modality in burn physiotherapy programmes. Burns. 2014 Aug 1;40(5):909-14.
19. Randoll UG, Hennig FF. Coherent Rhythms (Timing Frequencies) in Biological Systems as a Basis for the Matrix-Rhythm. Therapy. 2003.
20. Weinheimer-Haus EM, Judex S, Ennis WJ, Koh TJ. Low-intensity vibration improves angiogenesis and wound healing in diabetic mice. PloS one. 2014 Mar 11;9(3):e91355.
21. Yu CO, Leung KS, Jiang JL, Wang TB, Chow SK, Cheung WH. Low-Magnitude High-Frequency Vibration Accelerated the Foot Wound Healing of n5-streptozotocin-induced Diabetic Rats by Enhancing Glucose Transporter 4 and Blood Microcirculation. Scientific reports. 2017 Sep 14;7(1):11631.
22. Gailiūnienė L, Krutulytė G, Šiaučiūnaitė V, Savickas R, Venslauskas M. The effect of low frequency 2-10 Hz vibrations on blood circulation in lower extremities. Journal of Vibroengineering. 2017 Sep 30;19(6):4694-701.
23. Taspinar F, Aslan UB, Sabir N, Cavlak U. Implementation of matrix rhythm therapy and conventional massage in young females and comparison of their acute effects on circulation. The Journal of Alternative and Complementary Medicine. 2013 Oct 1;19(10):826-32.




How to Cite

Naik, V., Khatri, C. B., & BR, G. (2020). Effect of matrix rhythm therapy in Diabetic foot ulcer healing: A Case Report. Journal of Contemporary Medical Sciences, 6(4), 187–190. https://doi.org/10.22317/jcms.v6i4.774



Case Report