Association between Hypovitaminosis D3 and Type II Diabetes Mellitus of Iraqi Patients
AbstractObjective: This research has been carried out to evaluate the levels of [25(OH)D3] as well as the correlation between the deficiency levels with the risk of experiencing T2DM in sample of Iraqi population.
Methods: The levels regarding the 25-hydroxy vitamin D3 and the fasting blood sugar (FBG) have been estimated in group of 58 T2DM patients and 31 control subjects of age between (25 - 65 year). The 25-hydroxy vitamin D3 has been estimated via ELISA and fasting blood sugar (FBG) was measured spectrophotometrically.
Results: The levels of 25-hydroxy vitamin D3 have been considerably lower in individuals experiencing T2DM (9.465 ± 3.567 ng/ml) than in the control group (14.146 ± 11.045 ng/ml), (P = 0.02) whereas FBG levels were considerably higher in patients experiencing T2DM (218 ± 66 mg/dl) widespread in comparison to control group (89.8 ± 9 mg/dl), (P = 0.009). The levels related to the 25-hydroxy vitamin D3 are inversely related to FBG in both diabetic and control group (P = 0.01, r2 = 0.1), (P < 0.01, r2 = 0.2) respectively. VDD is considered to be related to the hazard of experiencing T2DM; also it is highly prevalent in subjects of Iraqi nationality.
Conclusion: VDD is associated to the risk of experiencing T2DM. hypovitaminosis D is very prevalent among the study participants and its percent was higher in female and have a therapeutic implications as cautious supplementation of vitamin D could enhance glycemic control in T2DM.
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