TY - JOUR AU - Al-Hisnawi, Maryam Sabah AU - Jabor, Mohammed Abdulla PY - 2016/01/08 Y2 - 2024/03/29 TI - Preparation of nanohybrid compound from the drugs (naproxen and cephalexin) with zinc oxide and studying biological activities against Aeromonas bacteria JF - Journal of Contemporary Medical Sciences JA - J. Contemp. Med. Sci. VL - 1 IS - 4 SE - Articles DO - UR - https://www.jocms.org/index.php/jcms/article/view/46 SP - 16-19 AB - <p>Objectives This study focus on the preparation of the compound nanoscale layers of Zinc oxide (ZnO) with naproxen and cephalexin.<br />Methods Ion exchange technique via sol-gel method synthesised under aqueous environment, resulted in the formation of inorganic organic<br />characteristics of nanohybrid by using X-ray diffraction (XRD) method and study antibacterial activity of hybrid and free compound against<br />some bacteria.<br />Results The powder X-ray diffraction showed new level for nanohybrid compounds differ from free compounds. The antibacterial results<br />show more nanohybrid compounds concentration increased its effectiveness against bacteria, the greater the concentration of the<br />compound greater is the increase in its effectiveness against bacteria inhibitory.<br />Conclusions The possibility of the bind of drugs (Cephalexin and Naproxen) in the preparation of nanohybrid-ZnO compound and the use<br />of nanocompounds as antibacterial agent in better treatment of pathogenic bacteria. And this nanocompound is more efficient from free<br />compounds.</p> ER -