@article{Al-Saadiaa_Naji_Al-Saadi_2016, title={Production and optimisation of hyaluronic acid extracted from Streptococcus pyogenes}, volume={1}, url={https://www.jocms.org/index.php/jcms/article/view/52}, abstractNote={<p>Objectives Because of the less studies in this field in Iraq, this study aimed to use local Streptococcus pyogenes isolates to produce hyluronic acid.<br />Methods The quantitative estimation of hyaluronic acid (HA) produced from eight local S. pyogenes isolates at different pH (6.3, 6.6, 6.9, 7.2,<br />and 7.5) and glucose concentration (4%, 6%, 8%, and 1%) were done using the HA ELISA kit.<br />Results This study showed that the maximum yield of HA was obtained at pH 7.5, and it was found that the differences in pH of the<br />production media of HA enhanced the HA production, but the glucose concentration has no beneficial effect for HA production.<br />Conclusion There were differences in HA production among local isolates at the same pH.</p>}, number={4}, journal={Journal of Contemporary Medical Sciences}, author={Al-Saadiaa, Kawkab Abdulla and Naji, Hassan Fadhil and Al-Saadi, Ali Hmood}, year={2016}, month={Jan.}, pages={13–15} }