Study the effect of Nigella Sativa on thyroid function and reproductive hormone of female rat

  • Wafaa Kadhim Jasim Department of Veterinary physiology and pharmacology, College of Veterinary Medicine, University of Karbala, Karbala, Iraq.
  • Mayada Sahib Hassan Department of Veterinary physiology and pharmacology, College of Veterinary Medicine, University of Karbala, Karbala, Iraq.
  • Ghsoon Ghanem Keam Department of Clinical Laboratories, College of Applied Medical Sciences, University of Karbala, Karbala, Iraq.

Abstract

Objectives The present study was conducted to investigate the effect of Nigella sativa on hormone reproduction and thyroid function in female rats.Methods Twelve females rats were used and divided randomly into two groups (6 animals for each) first group served as treatment and gave Nigella sativa oil (1ml /kg BW/day ) orally according to body weight for a period of 30 consecutive days. While other group drenched with normal saline at same dose that above mentioned and served as control.Results The result revealed significant increase in levels of LH, Estrogen T3 and T4 and significant decrease in level of TSH. Histological sections of thyroid gland revealed presence vaculation in colloid of thyroid follicle.Conclusion In conclusion, the Nigella sativa oil caused the elevation of thyroid hormones as well as LH and estrogen but still within normal value.
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Published
2016-06-30
How to Cite
JASIM, Wafaa Kadhim; HASSAN, Mayada Sahib; KEAM, Ghsoon Ghanem. Study the effect of Nigella Sativa on thyroid function and reproductive hormone of female rat. Journal of Contemporary Medical Sciences, [S.l.], v. 2, n. 6, p. 67-69, june 2016. ISSN 2413-0516. Available at: <http://www.jocms.org/index.php/jcms/article/view/75>. Date accessed: 26 may 2017.
Section
Articles

Keywords

Nigella sativa, rat, LH, T3, T4, TSH