Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome

Authors

  • Batool Luay Aziz Department of Biochemistry, College of Medicine, University of Karbala, Holy Karbala city
  • Ahmed Hussein Al-Mayali Department of Biochemistry, College of Medicine, University of Karbala, Holy Karbala city
  • Shaymaa Zahraw Nada Department of Biochemistry, College of Medicine, University of Karbala, Holy Karbala city
  • Fatemah Abdullah Mankhi Branch of Immunology Laboratory, in Al-Hussein Teaching Hospital, Al-Hussein Medical City/ Kerbela Health Directorate.

Abstract

Objectives This study aimed to investigate and measure the relationships between the adiponectin levels and oxidized-low density
lipoprotein (Ox-LDL) in acute coronary syndrome (ACS) patients in holy Kerbala city, Iraq.
Methods Fifty-eight patients included in the study. Patients admitted with a diagnosis of ACS and 30 control subjects. Circulating
adiponectin and Ox-LDL were assessed; using enzyme-linked immunosorbent assays (ELISA).
Results Adiponectin serum concentrations were signifcantly lower (p < 0.001) in subjects with ACS compared with control subjects.
Ox-LDL serum concentrations were signifcantly higher (p < 0.001) in subjects with ACS compared with controls subjects. The ACS patients
showed a signifcantly higher (p < 0.001) result in total cholesterol and signifcantly lower (p < 0.001) level in HDL-C.
Conclusion Serum adiponectin negatively correlated with Ox-LDL level in patient group ACS and the healthy control group.

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Published

2017-04-03

How to Cite

Aziz, B. L., Al-Mayali, A. H., Nada, S. Z., & Mankhi, F. A. (2017). Impact of adiponectin and oxidized low-density lipoprotein in acute coronary syndrome. Journal of Contemporary Medical Sciences, 3(9), 163–166. Retrieved from https://www.jocms.org/index.php/jcms/article/view/142

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Articles