Common clinical symptoms and concomitant disease in celiac patients – A large cohort study in the North-East of Iran
AbstractObjectives: This study aimed to provides an overview of large cohort focusing in different clinical symptoms and concomitant disease in CD patients.
Methods: Out of total 1,164 cases, 78.86% of cases were adults (mean age 29.67 ± 15.94) and sex ratio (f/m) was 2.40. Evaluated clinical characteristics included BMI, Marsh, TGA-IgA titer, main symptoms and concomitant disease.
Results: 96.86% of CD cases were seropositive anmore than 88% of patients had villous atrophy that 48.89% of them were type c. Dyspepsia 35.23%, diarrhea 18.52%, were main CD clinical symptoms. The common concomitant diseases were including nervous problems 57.43%, anemia 54.25%, osteopenia 28.23% and skin disease 23.54%.
Conclusion: the classic type is common type of CD in northeast Iran. Dyspepsia and diarrhea main clinical symptoms in these patients, consequence we recommended to screening for CD in cases whiteout classic symptoms (such as dyspepsia). Also recommended to screening for concomitant disease such as nervous problems, bon disease and anemia in female CD patients in first visit.
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