Efficacy of Intra-Articular Injection of Activated Platelet Rich Plasma as Pain Management Method in Chronic Knee Pain

  • Abdullah Ahmed Mohammad Department of Family Medicine, Azadi Teaching Hospital, Kirkuk, Iraq
  • Hayder Ghali Wadi Algawwam Department of Emergency Medicine, ONG Onlus, Sulaymaniyah, Iraq


Objective The aim of this retrospective study is to evaluate the efficacy of IA-PRP in managing the chronically painful knees with OA in a private clinic in Kirkuk, Iraq.
Methods Over an 18-month period (July 1, 2016- December 31, 2017), 76 patients (57 females) visited us because of painful knees due to OA. 124 knees received IA injections of ozonized PRP (OPRP). The PRP was prepared by centrifuging patients’ own blood and activated by passing 1 ml of ozone for each 1 ml of PRP. A questionnaire was used to categorize the pain into mild, moderate, and severe and the response to therapy was graded as excellent, good, fair and poor.
Results The mean age was 53.6± 1.7 years. 59.2% of females had a moderate pain. Overall, IA-PRP injection yielded excellent-good results in (88.7%) of the treated joints. More than half (n=53, 66.3%) of the well-responded joints received 1-4 doses of IA-OPRP. 
Conclusion IA-PRP seems to be an effective, safe and cheep method for relieving the chronic pain of knee OA.
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How to Cite
MOHAMMAD, Abdullah Ahmed; ALGAWWAM, Hayder Ghali Wadi. Efficacy of Intra-Articular Injection of Activated Platelet Rich Plasma as Pain Management Method in Chronic Knee Pain. Iraq Medical Journal, [S.l.], v. 2, n. 4, dec. 2018. ISSN 2521-8492. Available at: <http://www.jocms.org/index.php/imj/article/view/532>. Date accessed: 19 may 2019.