Effect of temporary examination stress on ceruloplasmin, copper, and iron levels in sera of academic students
AbstractObjective: Examination stress is a common and widespread phenomenon for students. So the main aim of this study was to check the effect of temporary examination stress on some biochemical parameters in sera of academic students.Methods: A total of 55 apparently healthy undergraduate students were enrolled in this study. Blood samples were collected two times from each student, at a written exam (E-day) and at the normal day (N-day). The serum Cp concentration and Cp ferroxidase activity were measured by spectrophotometry, while total serum copper and iron ions were measured by atomic absorption technique. The results were compared between E-day and N-day.Results: Significantly decrease (P < 0.05) were found in the serum Cp concentration, Cp ferroxidase activity, and total serum copper for all students. The total serum iron was significantly decreased (P < 0.05) in the female group.Conclusion: Cp ferroxidase activity was significantly decreased in E-day compared with N-day in response to releasing iron that accumulates in the liver. It may be an indicator of increasing oxidative stress in the sera of students in examination stress; also serum copper was significantly decreased in all undergraduate students in this comparison in response to antioxidant role of Cp.
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